Journal of modern medicine
Structural brain changes on MRI and their association with the severity of cognitive dysfunction in type 2 diabetes mellitus
By М.D. Fayzieva and М.М. Yakubova.
Abstract
Aim
To investigate and characterize MRI-detectable structural brain changes associated with cognitive impairment in patients with type 2 diabetes mellitus (T2DM).
Methods
This study included 61 patients with T2DM, stratified into three groups based on Mini-Mental State Examination (MMSE) score: severe cognitive impairment (Group I, n=20), mild-to-moderate cognitive impairment (Group II, n=26), and no cognitive impairment (Group III, n=15). All participants underwent brain MRI, with assessment of cortical atrophy, ventricular and subarachnoid space changes, and lacunar infarcts. Statistical analysis was performed using Jamovi software.
