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medRxiv
By Bonta, K. M., Corbett, E., Alemu, M. K. and 22 others.
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This study examined the extent to which educational attainment, Alzheimer's disease (AD) knowledge, and research attitudes are associated with willingness to participate in AD research, and whether AD knowledge and research attitudes mediate associations between educational attainment and willingness to participate.
201 older adults completed self-report measures of AD knowledge, research attitudes, prior research participation, and willingness to participate in diagnostic procedures (neuropsychological assessment, blood draw, brain MRI) and non-pharmacological intervention research (tracking physical activity, aerobic exercise).
Favorable research attitudes were consistently associated with greater willingness to participate across all proposed research activities, and research attitudes mediated the relationship between educational attainment and willingness to participate in research. In contrast, AD knowledge did not mediate the association between educational attainment and willingness to participate.
Research attitudes may be a key, modifiable determinant of willingness to participate in AD research and a promising focus for broadening AD research participation.
This is a preprint: it has not been peer reviewed yet, and its findings may change.
Published in medRxiv (preprint). The abstract is shown as published and remains the work of its authors; read the full article at the source.
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