medRxiv
Diagnostic Concordance of Immediate Versus 1-Hour Technetium-99m Hydroxymethylene Diphosphonate Scintigraphy in Suspected Transthyretin Amyloid Cardiomyopathy
By Costa, A., Suits, A., Miller, J. and 9 others.
Abstract
Background
Bone-avid tracer myocardial scintigraphy for transthyretin amyloid cardiomyopathy (ATTR-CM) traditionally employs 1- or 3-hour imaging intervals. Technetium-99m hydroxymethylene diphosphonate (99mTc-HDP) has unique kinetics that may enable earlier imaging. We investigated the diagnostic concordance of immediate versus 1-hour acquisitions.
