Preclinical assessment of central and peripheral anti-nociceptive effect of taraxerol acetate

Background

Successful management of pain remains a main clinical problem due to adverse effects caused with prolonged use of analgesics. This has motivated ongoing research into natural compounds that may possess therapeutic properties. A penta cyclic triterpene, Taraxerol acetate, has been reported to hold numerous biological activities; however, its analgesic properties have not been expansively appraised. The current study aimed to investigate using well-established experimental pain models in mice, the peripheral and central analgesic effects of taraxerol acetate.