ACE2 polymorphisms (RS6629110 and RS2106806) and severity of COVID 19 disease in mosul population of iraq

Background

The biggest challenge that humanity has faced since 2019 is the spread of the Covid 19 pandemic worldwide. The researchers focused more on the mechanism by which the spike (S) protein of the virus binding with the ACE2 receptor and then enters the host. Methodology: In the current study, 124 individuals of COVID-19 patients were classified into three groups, Mild (N=39), Moderate (=40), and Sever (N=45) cases. We used an amplification refractory mutation system (ARMS-PCR) for ACE2 (rs6629110 and rs2106806) genotyping.