Advances in Clinical Medical Research
Detection of autoimmune diseases in children by indirect immunofluorescence test in a paediatric tertiary care hospital
By Aysha Munna C, Udayasri B and K. Madhurima.
Abstract
Background
Autoimmune diseases in children often present with nonspecific manifestations, making early diagnosis challenging. Antinuclear antibody (ANA) testing by indirect immunofluorescence (IIFT) is useful for screening suspected autoimmune disorders. The aim is to detect autoimmune diseases in children by IIFT and correlate clinical diagnosis with laboratory findings. Materials and Methods: This cross-sectional study included 88 children with clinical suspicion of autoimmune disease at Niloufer Hospital for Women and Children, Hyderabad, from March to October 2023. Serum samples were tested by IIFT using HEp-2 and primate liver cells.
