Pharmaceutico-analytical study and invitro antimicrobial evaluation of polyherbal vaginal wash and vaginal suppository

Vaginitis is a common condition affecting millions of women worldwide, characterized by abnormal vaginal discharge and pruritus that can adversely affect physical and mental well-being. In Ayurveda, such conditions are described under Yoni Vyapath, where Vata, Lodhra, and Plaksha are traditionally used for management. Although conventional therapies are effective, they are often associated with microbial resistance, recurrent infections, and disruption of the normal vaginal flora. This study aimed to prepare and evaluate polyherbal vaginal wash and suppository formulations using hydroethanolic extracts of Vata, Lodhra, and Plaksha. The extracts were prepared by Soxhlet extraction, concentrated by rotary vacuum evaporation, and dried in a hot air oven. Three batches of vaginal wash and two batches of vaginal suppository were formulated, and one was selected based on the desirable characteristics.