Bridging Research and Innovation in Endoscopic Submucosal Dissection: A Publication-Patent Analysis Revealing Systematic Clinical-Technical Divergence

Objective

Clinical research and technological innovation are assumed to evolve in tandem through market-mediated knowledge diffusion, yet systematic evidence for their alignment in medical device domains remains limited. This study examines the relationship between the production of scientific evidence and the commercial development of devices for endoscopic submucosal dissection, a minimally invasive treatment for gastrointestinal neoplasms, which has experienced uneven global diffusion.