Association between Perinatal Risk Factors and Incidence of Culture-proven EOS in Preterm Neonates Born Before 34 Weeks – A Retrospective Cohort Study

A BSTRACT Background: Preterm neonates are often started on empirical antibiotics for early-onset sepsis (EOS), based on the presence of perinatal risk factors. The relevance of this approach is not well known in low-and middle-income countries, where Gram-negative pathogens are prevalent.