Asian Pacific Journal of Tropical Medicine
Predictors of treatment failure in pediatric toxocariasis: A two-part study in Ho Chi Minh City, Vietnam
By Văn Thiệu Hà, Huy Khoi Ha, Văn Bách Ngô and 2 others.
Abstract
Objective
To identify factors associated with the therapeutic effectiveness of albendazole in children with Toxocara canis infection in Ho Chi Minh City, Vietnam.
Methods
The study was conducted from April 2022 to December 2023 and consisted of two phases. Phase 1 was a cross-sectional study involving 986 children aged 3-15 years in Ho Chi Minh City, Vietnam, to determine the seroprevalence of Toxocara spp. using ELISA IgG testing. Phase 2 was an interventional study conducted in children with compatible clinical manifestations and positive ELISA results. Patients received albendazole at a dose of 15 mg/kg/day for 5 days. Clinical and laboratory reassessments were performed 6 months after treatment.
