WSEAS TRANSACTIONS ON BIOLOGY AND BIOMEDICINE
ABO and Rh Hemolytic Disease of the Fetus and Newborn
By Shorena Gabaidze, Marina Nagervadze, Leila Akhvlediani and 4 others.
Abstract
Hemolytic disease of the fetus and newborn (HDFN) is a blood disorder in which red blood cells are destroyed faster, leading to anemia. Our study focused on immune-mediated HDFN. The study included 86 newborns with HDFN. Samples were provided to two clinics in Georgia. Coombs tests were performed to confirm the presence of HDFN. Monoclonal antibodies were used to determine ABO and Rh blood group antigens. The genetic analysis was performed using the SNP rs8176719. ABO-HDFN was the majority, followed by Rh-HDFN (χ2 = 6.44, p = 0.04). the majority newborns with ABO-HDFN have A(II), Rh+ blood group (χ2 =141.16, p
Keywords
- Blood groups and transfusion
- ABO blood group system
- Rh blood group system
- Fetus
- Haemolytic disease
- Hemolytic disease of the newborn (ABO)
- Antibody
- Disease
- Blood type (non-human)
- Open access
Source
Published in WSEAS TRANSACTIONS ON BIOLOGY AND BIOMEDICINE. The abstract is shown as published and remains the work of its authors; read the full article at the source.
