Metabolites
Metabolic and Thyroid Alterations in HBV Monoinfection and HBV–HDV Coinfection: Insights from a Liver Transplant Cohort
By Ayfer Serin, Safiye Koçulu Demir, Birkan Bozkurt and 3 others.
Abstract
Background
Metabolic alterations associated with hepatitis B virus (HBV)–hepatitis D virus (HDV) coinfection remain poorly characterized. We investigated metabolic and endocrine profiles in HBV monoinfection and HBV–HDV coinfection, with emphasis on quantitative HDV activity.
Methods
This retrospective observational study included HBsAg-positive adult liver transplant candidates. Pre-transplant metabolic, biochemical, thyroid, and virological parameters were evaluated. Associations between quantitative HDV RNA and metabolic parameters were assessed using Spearman correlation and multivariable regression.
