Real-World Effectiveness and Safety of Esomeprazole/Magnesium Hydroxide in Gastroesophageal Reflux Disease: Results from a Multicenter Prospective Observational Study

Background/Objectives: Proton pump inhibitors (PPIs) are the mainstay treatment for gastroesophageal reflux disease (GERD); however, variability in treatment response and suboptimal symptom control pose clinical challenges. This study aimed to evaluate the real-world effectiveness and safety of esomeprazole/magnesium hydroxide in patients with GERD using a structured symptom assessment.