Topical Hyaluronic Acid for Palatal Donor-Site Healing After Autogenous Gingival Graft Harvesting: A Systematic Review and Time-Specific Meta-Analysis with Clinical Implications for Postoperative Care

Background

Palatal graft harvesting can cause pain, bleeding, and delayed healing, with postoperative recovery varying across patients and over time. Topical hyaluronic acid (HA) may reduce donor-site morbidity and promote tissue repair. Identifying the postoperative time points and clinical domains in which HA may provide benefit could support more informed, patient-centered postoperative management.