Safety and Preliminary Clinical Outcomes of Silver Ion-Doped Calcium Phosphate-Coated Orthopedic Implants: A Prospective Pilot Study

Background

Implant-related infections remain a major cause of failure in orthopedic surgery, partly because biofilm formation on implant surfaces limits conventional infection-control strategies. This prospective pilot study evaluated the short-term safety and preliminary anti-infective performance of silver ion-doped calcium phosphate-coated orthopedic implants.