Association and Incremental Discriminative Value of Four Estimated Muscle-Related Indices for Progression from Prediabetes to Type 2 Diabetes Mellitus: A Retrospective Cohort Study with up to 10 Years of Follow-Up

Objective

This study examined the associations of four estimated muscle-related indices (height-adjusted appendicular skeletal muscle mass [ASM/height2], weight-adjusted ASM [ASM/weight], predicted skeletal muscle mass index [pSMI], and creatinine-to-cystatin C ratio [CCR]) with progression from prediabetes to type 2 diabetes mellitus (T2DM) and compared their preliminary predictive performance.