How Endpoint Definitions Shape Epidemiologic Inference on Tuberculosis Treatment Outcomes: A Secondary Analysis from Lima, Peru

Background/Objectives: Tuberculosis treatment outcomes are often dichotomized into heterogeneous composites that may obscure outcome-specific associations. We compared baseline characteristics across mutually exclusive out-comes—loss to follow-up (LTFU), death, and not evaluated/transferred versus documented cure—and examined the composite endpoints secondarily in a prospective cohort of adults with smear-positive pulmonary tuberculosis treated in Lima, Peru, in 2010–2011.