Diagnostics
Associations and Discriminatory Performance of Anthropometric and Body-Shape Indices for Identifying Hypertension in Adults with Type 2 Diabetes in Malawi: A Cross-Sectional Study
By Alexander Thomas Mboma, Saulos Kondwani Nyirenda, Kondwani Joseph Banda and 3 others.
Abstract
Background
We evaluated the discriminatory performance of traditional anthropometric parameters and novel body-shape indices for identifying hypertension among adults with type 2 diabetes mellitus (T2DM) in Malawi.
Methods
This was a multicenter cross-sectional study of 1356 adults with T2DM attending outpatient diabetes clinics at three tertiary referral hospitals. Traditional anthropometric parameters were body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR). Novel body-shape indices were the weight-adjusted waist index (WWI), a body shape index (ABSI), the conicity index, and body roundness index (BRI). Hypertension was defined as systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg, or current antihypertensive medication use. Multivariable logistic regressions and receiver operating characteristic (ROC) analyses were performed overall and, as secondary subgroup analyses, stratified by sex; effect modification by sex was tested formally using interaction terms.
