Diagnostics
Growth and Pubertal Status in Children with Type 1 Diabetes: A Cross-Sectional Comparison with Non-Diabetic Controls
By Monica Simina Mihuţa, Dana Liana Stoian, Denisa Pescari and 6 others.
Abstract
Background/Objectives: Type 1 diabetes mellitus (T1DM) has historically been associated with impaired linear growth and delayed pubertal development due to chronic insulin deficiency. Advances in intensive insulin therapy and glucose monitoring may have substantially reduced these effects. This study evaluated growth and pubertal development in children with T1DM treated with multiple daily injections (MDIs) or continuous subcutaneous insulin infusion (CSII) compared with non-diabetic controls and investigated whether metabolic control was associated with anthropometric outcomes.
