Investigation of the Immunological Profile of Children with Infectious Mononucleosis

Background/Objectives: This study aimed to characterize the cell-mediated immune (CMI) profile—peripheral lymphocyte subsets, a 14-cytokine panel, and intracellular granzyme B/perforin expression—in children with acute IM compared with age- and sex-matched healthy controls, and to describe its dynamics at symptom resolution in an exploratory paired subset. This is a descriptive, hypothesis-generating study.