China National GeneBank DataBase
Integrative analysis of plasma cell-free RNA and gut microbiome enables early prediction of GDM
By 叶庆实(Qingshi Ye).
Abstract
Gestational diabetes mellitus (GDM) diagnosis at 24 to 28 gestational weeks limits early intervention. Integrating host transcriptomes with microbial signatures captures both systemic and environmental alterations for improved early prediction. In a nested case and control longitudinal study of 694 pregnant women sampled across three trimesters, profiling of plasma cell free transcriptome and gut microbiome microbial revealed alternations associated with GDM.
Keywords
- Gestational Diabetes Research and Management
- Transcriptome
- Gestational diabetes
- Microbiome
- Gut flora
- Gut microbiome
- RNA
- Metagenomics
- Gene expression profiling
- Fetus
- Open access
Source
Published in China National GeneBank DataBase. The abstract is shown as published and remains the work of its authors; read the full article at the source.
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