Proteomic characterization of adult Fasciola gigantica recovered from naturally infected buffaloes in Punjab Pakistan

Background

Fasciola gigantica (F. gigantica) is a widespread zoonotic trematode that poses a substantial burden on livestock and public health in endemic regions. Elucidating host-parasite interactions relies largely on proteomic data. Excretory-Secretory proteins (ESPs) can play central roles in the host-parasite interactions, immune evasion, and parasite pathogenicity; however, proteomic information on F. gigantica infecting buffalo remains scarce, particularly from Pakistan.