GE Portuguese Journal of Gastroenterology
Detecting Early Liver Fibrosis in Obesity: A Head-to-Head Comparison of Five Clinical Scores in Metabolic Dysfunction-Associated Steatotic Liver Disease / Detecção Precoce de Fibrose Hepática na Obesidade: Comparação Direta de Cinco Scores Clínicos na Doença Hepática Esteatótica Associada à Disfunção Metabólica
By Giovani Schulte Farina, Bárbara Brambilla, Laura Kalil Nader Lazzaretti and 13 others.
Abstract
Introduction
Obesity is a major driver of metabolic dysfunction-associated steatotic liver disease (MASLD) and liver fibrosis, creating an urgent need for accurate, non-invasive tools to identify fibrosis in this high-risk population. We compared five clinical fibrosis scores (FIB-4, NFS, APRI, BARD, Hepamet) for detecting any fibrosis (F1–F4) in obese individuals at risk of MASLD and to assess whether metabolic syndrome (MetS) modifies score performance.
