JAIDS Journal of Acquired Immune Deficiency Syndromes
At-Home Point-of-Care Urine Tenofovir Testing for Adherence Monitoring: Feasibility and Comparison with Adherence Metrics in Dried Blood Spots
By Renata Buccheri, Matthew A. Spinelli, Parya Saberi and 5 others.
Abstract
Background
Scalable, low-cost strategies for monitoring antiretroviral therapy adherence are increasingly important, particularly in decentralized and telehealth-based care settings. This study assessed both the feasibility and performance of at-home, point-of-care (POC) urine tenofovir (TFV) testing for adherence monitoring, using tenofovir diphosphate (TFV-DP) levels in dried blood spots (DBS) as a pharmacological standard of adherence.