Redox Biology
HDAC1-mediated SUCLA2 lysine β-hydroxybutyrylation modulates myocardial mitochondrial function in sepsis-induced heart dysfunction
By Ri Wen, Wanshan Ning, Xin-Mei Huang and 8 others.
Abstract
Background
Lysine β-hydroxybutyrylation (Kbhb) is associated with energy regulation and mitochondrial function, and its role in sepsis-induced heart dysfunction has not been elucidated.
Objectives
Reveals the extensive effects of Kbhb in sepsis-induced heart dysfunction and identifies the potential targets.