B-108: Efficacy of Computerized Cognitive Training on Cognitive Outcomes in Individuals With Traumatic Brain Injury: A Systematic Literature Review

Abstract Objective: This systematic review evaluated the efficacy of computerized cognitive training on cognitive outcomes in individuals with traumatic brain injury (TBI). The review examined intervention effects across neurocognitive domains, given persistent cognitive impairments following TBI and increasing use of technology-based rehabilitation approaches. Method/Data Selection: A systematic literature review was conducted using PubMed, PsycINFO and the Cochrane Library to identify peer-reviewed studies published between 2014 and 2026. Search terms were combined using Boolean operators. Search terms included “traumatic brain injury”, “computerized cognitive training”, “cognitive rehabilitation”, “virtual reality”, and “cognitive outcomes”. Studies were included if they involved adults with TBI and evaluated computerized or technology-based cognitive interventions with reported post-intervention cognitive outcomes. Studies were excluded if they included pediatric populations or examined cognitive impairment attributable to non-acquired brain injury conditions. The initial search yielded 88 articles; after screening and applying inclusion criteria, nine studies were included. These comprised randomized controlled trials, randomized pilot study, controlled trials, quasi-experimental designs, and retrospective analyses. Results/Data Synthesis: Computerized cognitive training was associated with improvements in attention, processing speed, and working memory. Virtual reality interventions demonstrated benefits in attention and cognitive flexibility, while targeted programs improved social cognition. Several studies reported gains in quality of life and reductions in depressive symptoms. Findings for executive functioning were mixed. Results were synthesized using a qualitative narrative approach. Conclusions: Computerized cognitive training demonstrated effectiveness for improving specific cognitive domains (i.e., attention, processing speed, executive functioning and working memory) following TBI, with additional benefits in quality of life and mood. Further high-quality, longitudinal studies are needed to determine long-term efficacy and generalizability.