Scientific Reports
TransLPQPHOG: a new exemplar feature extraction model for intertrochanteric hip fracture detection
By Ömer Esmez, Şükrü Demir, Oguz Kaya and 5 others.
Abstract
Automated detection of intertrochanteric hip fractures from radiographs is constrained by the limited size of available datasets and the poor interpretability of many learning-based models. Here we develop TransLPQPHOG, a compact feature-engineering framework that integrates fixed local image patches, local phase quantization, pyramid histograms of oriented gradients, cumulative weighted iterative neighbourhood component analysis and multilayer perceptron classification. Each 224× 224-pixel radiograph was partitioned into a 14 × 14 grid of non-overlapping 16 × 16-pixel patches. This representation generated 83,104 features, of which 659 were retained for classification. We evaluated the framework in a retrospective single-centre cohort of 470 anteroposterior radiographs from 470 patients, comprising 226 intertrochanteric fracture cases and 244 controls. Image-level tenfold cross-validation was patient-disjoint because each patient contributed only one radiograph. Within every outer fold, min–max normalization, CWINCA ranking, feature-subset selection and MLP fitting were performed using the training partition only; the held-out fold was used only for testing. TransLPQPHOG achieved an accuracy of 90.85% (95% confidence interval, 87.90–93.14%), a sensitivity of 91.59%, a specificity of 90.16% and an area under the receiver operating characteristic curve of 0.9615. Under the same validation protocol, whole-image LPQ–PHOG achieved 72.77% accuracy, whereas patch-based configurations achieved accuracies ranging from 77.87% to 88.30%. The complete framework therefore provided the highest classification performance. Shapley analysis further showed that PHOG features accounted for 89.5% of the total absolute feature contribution, indicating that local gradient structure was the principal source of discriminative information. These findings demonstrate that interpretable patch-based feature engineering can support accurate internal classification of intertrochanteric hip fractures in a limited-data setting. However, the results do not establish clinical generalizability, and independent multicenter and prospective validation is required before clinical application.







