JHLT Open
Enhanced structural reverse remodeling following LVAD support in patients with
By Donald Richards, MD, MPH, Robert M. Cole, MD, Michelle Kittleson, MD, PhD and 8 others.
Abstract
Background
Myocardial recovery sufficient for left ventricular assist device (LVAD) explantation remains uncommon. Titin truncating variant (TTNtv)-associated cardiomyopathy demonstrates favorable reverse remodeling with medical therapy, but its remodeling potential during durable mechanical unloading is unknown.