Incidental discovery of a penile schwannoma during varicocelectomy: A rare case report

Penile schwannoma is an exceptionally rare benign peripheral nerve sheath tumor, with fewer than 40 cases reported in the literature. We present the case of a 37-year-old man in whom a 1-cm penile nodule was incidentally discovered during varicocele repair surgery. The lesion was completely excised and histopathological examination demonstrated characteristic Antoni A and Antoni B areas, Verocay bodies, and hyalinized vascular walls. Immunohistochemistry showed strong S-100 positivity, confirming the diagnosis of schwannoma. This case highlights the diagnostic role of histopathology and immunohistochemistry and the excellent outcome following complete surgical excision.

Published in Urology Case Reports. The abstract is shown as published and remains the work of its authors; read the full article at the source.

doi.org/10.1016/j.eucr.2026.103624