Respirology Case Reports
Erlotinib‐Induced Pneumatosis Intestinalis: A Case Report and Review of Literature
By Shunsuke Saito, Koki Nakashima, Kaede Yokoyama and 4 others.
Abstract
ABSTRACT Pneumatosis intestinalis (PI) is a rare condition characterized by gas accumulation within the bowel wall. Although several medications have been associated with the etiopathogenesis of PI, the association between PI and epidermal growth factor receptor ( EGFR )–tyrosine kinase inhibitors (TKIs) is less recognized. We present the case of a 79‐year‐old woman who developed PI 2 months after the initiation of erlotinib. The condition improved after the discontinuation of erlotinib, suggesting a possible association between erlotinib and the development of PI. This case underscores the importance of considering PI in the differential diagnosis when patients receiving EGFR ‐TKIs present with abdominal symptoms or intramural bowel gas.
Keywords
- Abdominal vascular conditions and treatments
- Open access
Source
Published in Respirology Case Reports. The abstract is shown as published and remains the work of its authors; read the full article at the source.
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