Barriers and Factors Associated With Disclosure of Chlamydia trachomatis Infection Among Sexually Active Individuals in Buea, Cameroon: A Cross‐Sectional Study

ABSTRACT Background Chlamydia trachomatis remains a major global public health concern, particularly among sexually active adolescents and young adults. Disclosure of an infection to sexual partners is essential for effective management and reduction of onward transmission; however, barriers to disclosure and communication persist. Objective This study assessed the proportion of participants willing to disclose a positive Chlamydia trachomatis result, the barriers to disclosure, and the factors associated with intended disclosure among sexually active individuals in Buea. Methods This community‐based, mixed‐methods cross‐sectional study was conducted from February to April 2024 among 253 participants aged ≥ 15 years recruited through convenience sampling. Structured questionnaires and in‐depth interviews captured sociodemographic characteristics, sexual behaviours, and perceived disclosure barriers. Quantitative data were analysed using descriptive statistics, Chi‐square tests, and multivariable logistic regression, while qualitative data were analysed thematically. Analyses were performed using SPSS version 26.0, with statistical significance set at p < 0.05. Results The participants' mean age was 24.2 years (SD = 4.85); most were female (64.0%) and single (89.3%). Overall, 68 participants (26.9%) indicated that they would not disclose a positive Chlamydia result, corresponding to approximately one in four participants. Major barriers included anxiety (13.1%), lack of communication (6.1%), fear of stigma, and anticipated negative partner reactions. Participants who anticipated a violent partner reaction were significantly less likely to disclose (AOR = 0.259, 95% CI: 0.109–0.615, p = 0.002), as were those who were uncertain about their partner's reaction (AOR = 0.401, 95% CI: 0.171–0.943, p = 0.036). Females had higher odds of intended disclosure than males (AOR = 1.93, 95% CI: 1.072–3.475, p = 0.028). Casual sex and inconsistent condom use were not significantly associated with intended disclosure. Conclusion Intended disclosure of Chlamydia trachomatis infection was constrained by psychosocial and relational barriers in Molyko. Interventions should prioritise stigma reduction, partner communication support, and community‐based education to improve disclosure practices and reduce transmission among populations at risk.