Pharmaceuticals
Cardioprotective and Antioxidant Effects of Marine-Derived Xestospongia testudinaria in an Isoprenaline-Induced Rat Model of Heart Failure
By Rajasegar Anamalley, Iman Nabilah Abd Rahim, Siti Nurhannah Irdina Hasmar Honiz and 7 others.
Abstract
Background
Oxidative stress and maladaptive cardiac remodeling are key contributors to heart failure progression. Xestospongia testudinaria, a marine sponge rich in bioactive compounds, possesses antioxidant and lipid-modulating properties. This study investigated the cardioprotective and antioxidant effects of Xestospongia testudinaria methanolic extract (Xesto) in an isoprenaline-induced rat model of heart failure.
