Journal of Ayurveda and Integrative Medicine
Antidiabetic potential of a novel hydroxyphenyl-bi-benzopyran-hexol compound from Cassia fistula as an α-amylase inhibitor: Integrated in silico screening and in vitro validation using a nonlinear regression model
By Rajamanickam Baskar, Manoharan Harini, Sikkal Selvaraaju Selvapriya and 5 others.
Abstract
Background
Diabetes mellitus is a critically important metabolic disease, causing persistent hyperglycemia. Blood glucose levels can be effectively maintained by inhibiting the activity of α-amylase. α-amylase inhibitors manage postprandial hyperglycemia by delaying carbohydrate digestion.