Brain Trauma Foundation
The use of mannitol in severe head injury. Brain Trauma Foundation
Abstract
Mannitol is effective in reducing ICP, and we recommend its use in the management of traumatic intracranial hypertension. Serum osmolalities greater than 320 mOSsm/L and hypovolemia should be avoided. Some data suggest that bolus administration is preferable to continuous infusion.
Source and rights
Published by Journal of neurotrauma, 1996. The guideline itself is at the source linked here.
Prognia summarises this guideline for reference and education. It is not medical advice. Always check the official guideline and current local protocols before acting on it.
At a glance
- Organisation
- Brain Trauma Foundation
- Published
- 1996
- Applies to
- 🇺🇸 United States
- Scope
- National
- Journal
- Journal of neurotrauma
- PubMed
- 8941889
- Added to Prognia
- 24 July 2026








