Journal of clinical pharmacy and therapeutics
The impact of guidelines on peri-operative antibiotic administration
Abstract
A survey has shown that peri-operative antibiotic therapy was inappropriate in 83% of patients undergoing abdominal or arterial surgery. Missed doses at induction or postoperatively, a questionable choice of antibiotics and unnecessarily long postoperative courses were major problems. The introduction of formal guidelines was partially successful with appropriate prescribing improving from 17 to 60% of cases. There was, in addition, a marked reduction in prescribing costs.
Source and rights
Published by Journal of clinical pharmacy and therapeutics, 1991. The guideline itself is at the source linked here.
Prognia summarises this guideline for reference and education. It is not medical advice. Always check the official guideline and current local protocols before acting on it.
At a glance
- Published
- 1991
- Applies to
- 🇬🇧 United Kingdom
- Scope
- National
- Journal
- Journal of clinical pharmacy and therapeutics
- PubMed
- 2026666
- Added to Prognia
- 16 July 2026



