Brain Trauma Foundation
The Brain Trauma Foundation. The American Association of Neurological Surgeons. The Joint Section on Neurotrauma and Critical Care. Guidelines for cerebral perfusion pressure
Abstract
Maintenance of a CPP above 70 mm Hg is a therapeutic option that may be associated with a substantial reduction in mortality and improvement in quality of survival and is likely to enhance perfusion to ischemic regions of the brain following severe TBI. No study has demonstrated that the incidence of intracranial hypertension, morbidity, or mortality is increased by the active maintenance of CPP above 70 mm Hg, even if this means normalizing the intravascular volume or inducing systemic hypertension.
Source and rights
Published by Journal of neurotrauma, 2000. The guideline itself is at the source linked here.
Prognia summarises this guideline for reference and education. It is not medical advice. Always check the official guideline and current local protocols before acting on it.
At a glance
- Organisation
- Brain Trauma Foundation
- Published
- 2000
- Applies to
- 🇺🇸 United States
- Scope
- National
- Journal
- Journal of neurotrauma
- PubMed
- 10937893
- Added to Prognia
- 25 July 2026






