Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Specificities of clinical research in radiotherapy
Abstract
The aim of this review is to present the specificities of clinical research in radiation oncology. Objectives are similar to all research in oncology: to improve the efficacy and to decrease toxic effects. Phase III trials remain the main methodology to demonstrate an improvement in efficiency, but phase I-II and registers are also important tools to validate an improvement in the therapeutic index with new technologies. In this article we discuss the special features of end-points, selection of population, and design for radiation oncology clinical trials. Quality control of delivered treatments is an important component of these protocols. Financial issues are also discussed, in the particular context of France.
Source and rights
Published by Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2022. The guideline itself is at the source linked here.
Prognia summarises this guideline for reference and education. It is not medical advice. Always check the official guideline and current local protocols before acting on it.
At a glance
- Published
- 2022
- Applies to
- 🇪🇺 Europe
- Scope
- Regional
- Journal
- Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
- PubMed
- 34953712
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