American Society of Hematology 2026 guidelines for frontline management of acute lymphoblastic leukemia in adolescents and young adults

Adolescents and young adults (AYAs) with acute lymphoblastic leukemia (ALL) represent a unique population. Treatment regimens can vary significantly depending on whether they receive care in a pediatric or in an adult setting. They also have distinctive care needs, social risk factors, and disease behavior compared with other age groups.