Advancing Guideline Methodology in Interventional Radiology: Introduction of the Clinical Care Recommendation Framework

The Society of Interventional Radiology (SIR) has introduced the Clinical Care Recommendation (CCR) framework to improve the development and communication of clinical guidelines in interventional radiology (IR). This framework combines rigorous evidence assessment with practical clinical decision-making to better reflect the complexities of IR practice. Recommendations are assigned a CCR strength (Strong, Moderate, Limited, No Benefit, Potential Harm) alongside a GRADE certainty rating, with wording aligned to strength categories for clear clinical interpretation.