American College of Obstetricians and Gynecologists
ACOG practice bulletin. Prevention of Rh D alloimmunization. Number 4, May 1999 (replaces educational bulletin Number 147, October 1990). Clinical management guidelines for obstetrician-gynecologists. American College of Obstetrics and Gynecology
Abstract
The reduction in the incidence of Rh D alloimmunization is a prototype for the effectiveness of preventive medicine. Some controversies remain, however, such as the use of anti-D immune globulin in patients with either threatened abortion or antenatal hemorrhage. Similarly, it may not be cost-effective either to screen all Rh D-negative patients with an indirect Coombs test at 24-28 weeks of gestation or to screen all postpartum patients for excessive fetomaternal hemorrhage.
Source and rights
Published by International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1999. The guideline itself is at the source linked here.
Prognia summarises this guideline for reference and education. It is not medical advice. Always check the official guideline and current local protocols before acting on it.
At a glance
- Organisation
- American College of Obstetricians and Gynecologists
- Published
- 1999
- Applies to
- 🇺🇸 United States
- Scope
- National
- Journal
- International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
- PubMed
- 10458556
- Added to Prognia
- 25 July 2026





