Adverse drug reaction

An adverse drug reaction is an unintended harmful reaction attributable to a medicine at doses normally used therapeutically. It can occur despite correct administration and does not necessarily imply a medication error.

An immune-mediated drug reaction is a drug {{c1::allergy}}.

Tolerance Physiological dependence

Key distinction · Reduced response with repeated exposure · Withdrawal symptoms can occur when the drug is removed

Physiological drug dependence

Physiological drug dependence is an adaptation during sustained exposure such that removal of the drug can produce physical withdrawal symptoms.

Drug accumulation toxicity

Drug accumulation toxicity is harm caused by excessive accumulation of a drug; it can occur when elimination is impaired while drug input continues.

Principles of Pharmacology — Flashcards — Mazos de tarjetas médicas

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