International journal of endocrinology
Association Between Lipid Accumulation Product and Visceral Adiposity Index, as Markers of Visceral Adiposity and Metabolic Dysfunction, and Stroke: NHANES 1999-2018
Por Zhou Q y Zhang Z.
Contenido en inglés
Resumen
Aims
Lipid accumulation product (LAP) and visceral adiposity index (VAI) are surrogate markers of visceral adiposity-related endocrine and metabolic dysfunction, including insulin resistance, rather than simple obesity indices. This study aimed to evaluate their associations with stroke prevalence using nationally representative data.
Materials and methods
This cross-sectional study analyzed data from the National Health and Nutrition Examination Survey (NHANES) 1999-2018. Stroke status was determined through standardized questionnaires. LAP and VAI were calculated using established gender-specific formulas. Analyses used the fasting subsample weights with strata and primary sampling units, and missing covariates were multiply imputed. Weighted logistic regression, restricted cubic spline (RCS), subgroup and incremental discrimination analyses were performed.