Concurrent biliary atresia and intestinal atresia: a systematic review of clinical characteristics, pathogenesis, management, and outcomes

The coexistence of biliary atresia (BA) and intestinal atresia (IA) is exceptionally rare. Delayed recognition of BA in neonates undergoing surgery for IA may adversely affect outcomes. This systematic review aimed to evaluate the available evidence regarding the clinical presentation, pathogenesis, management strategies, and outcomes of patients with concurrent BA and IA.

A systematic literature search of PubMed, MEDLINE, and Google Scholar was conducted for studies published up to December 2025. Relevant studies encompassing case reports, case series, and retrospective reviews were identified. Data regarding demographics, type of intestinal atresia, associated anomalies, diagnostic methods, surgical management, and outcomes were extracted.