Efficacy and Safety of Pioglitazone in Improving Cognitive Function Among Stroke Patients: A Prospective, Double-Blind, Randomized Controlled Trial

Introduction

Stroke patients are at a higher risk of developing cognitive difficulties. Insulin resistance has been identified as a risk factor for decline in cognition, raising the possibility that pioglitazone, an insulin-sensitizing agent, might benefit stroke patients with cognitive impairment by improving insulin sensitivity.