FDA

Succinylcholine Chloride

Approved 16 Jun 2020InjectionInjectable

The FDA lists this product in 30 strengths and forms.

Indications

Succinylcholine Chloride Injection is indicated in adults and pediatric patients:

as an adjunct to general anesthesia
to facilitate tracheal intubation
to provide skeletal muscle relaxation during surgery or mechanical ventilation. Succinylcholine Chloride Injection is a depolarizing neuromuscular blocker indicated in adults and pediatric patients:
as an adjunct to general anesthesia ( 1 )
to facilitate tracheal intubation ( 1 )
to provide skeletal muscle relaxation during surgery or mechanical ventilation. ( 1 )

Succinylcholine chloride injection is contraindicated:

in patients with skeletal muscle myopathies [see Warnings and Precautions (5.1) ]
in patients with known hypersensitivity to succinylcholine. Severe anaphylactic reactions to succinylcholine have been reported [see Warnings and Precautions (5.2) ]
after the acute phase of injury following major burns, multiple trauma, extensive denervation of skeletal muscle, or upper motor neuron injury, which may result in severe hyperkalemia and cardiac arrest [see Warnings and Precautions (5.4) ]
in patients with known or suspected genetic susceptibility to malignant hyperthermia [see Warnings and Precautions (5.5) , Clinical Pharmacology (12.5) ]
Skeletal muscle myopathies ( 4 )
Known hypersensitivity to succinylcholine ( 4 )
After the acute phase of injury following major burns, multiple trauma, extensive denervation of skeletal muscle, or upper motor neuron injury ( 4 )
Known or suspected genetic susceptibility to malignant hyperthermia ( 4 )

Anaphylaxis : Severe anaphylactic reactions to neuromuscular blocking agents, including succinylcholine, have been reported. Some cases have been life-threatening and fatal. Take necessary precautions, such as the immediate availability of appropriate emergency treatment. ( 5.2 )

Indications

Succinylcholine Chloride Injection is indicated in adults and pediatric patients:

as an adjunct to general anesthesia
to facilitate tracheal intubation
to provide skeletal muscle relaxation during surgery or mechanical ventilation. Succinylcholine Chloride Injection is a depolarizing neuromuscular blocker indicated in adults and pediatric patients:
as an adjunct to general anesthesia ( 1 )
to facilitate tracheal intubation ( 1 )
to provide skeletal muscle relaxation during surgery or mechanical ventilation. ( 1 )

Contraindications

Succinylcholine chloride injection is contraindicated:

in patients with skeletal muscle myopathies [see Warnings and Precautions (5.1) ]
in patients with known hypersensitivity to succinylcholine. Severe anaphylactic reactions to succinylcholine have been reported [see Warnings and Precautions (5.2) ]
after the acute phase of injury following major burns, multiple trauma, extensive denervation of skeletal muscle, or upper motor neuron injury, which may result in severe hyperkalemia and cardiac arrest [see Warnings and Precautions (5.4) ]
in patients with known or suspected genetic susceptibility to malignant hyperthermia [see Warnings and Precautions (5.5) , Clinical Pharmacology (12.5) ]
Skeletal muscle myopathies ( 4 )
Known hypersensitivity to succinylcholine ( 4 )
After the acute phase of injury following major burns, multiple trauma, extensive denervation of skeletal muscle, or upper motor neuron injury ( 4 )
Known or suspected genetic susceptibility to malignant hyperthermia ( 4 )