Potassium Chloride 40MEQ in Dextrose 5% and Sodium Chloride 0.45% in Plastic Container

Potassium Chloride in Dextrose and Sodium Chloride Injection is indicated as a source of water, electrolytes and calories. Potassium Chloride in Dextrose and Sodium Chloride Injection is indicated as a source of water, electrolytes and calories. ( 1 )

Potassium Chloride in Dextrose and Sodium Chloride Injection is contraindicated in patients with:

• known hypersensitivity to potassium chloride, dextrose and/or sodium chloride [see Warnings and Precautions 5.1) ]
• clinically significant hyperkalemia [see Warnings and Precautions (5.2) ]
• clinically significant hyperglycemia [see Warnings and Precautions (5.3) ]
• Known hypersensitivity to potassium chloride, dextrose, or sodium chloride ( 4 , 5.1 )
• Clinically significant hyperkalemia ( 4 , 5.2 )
• Clinically significant hyperglycemia ( 4 , 5.3 )

• Hypersensitivity Reactions : monitor for signs and symptoms and discontinue infusion if reactions occur. ( 5.1 )
• Hyperkalemia : May result in cardiac arrhythmias. Avoid use in patients with, or at risk for, hyperkalemia. If use cannot be avoided, use a product with a low amount of potassium chloride, infuse slowly and monitor serum potassium concentrations and ECGs. ( 5.2 )
• Hyperglycemia or Hyperosmolar Hyperglycemic State : Monitor blood glucose and administer insulin as needed. ( 5.3 , 8.4 )
• Hyponatremia, Hypernatremia and Hyperchloremia : Avoid in patients with or at risk for hypo-/hypernatremia. If use cannot be avoided, monitor serum sodium concentrations. ( 5.4 , 5.5 , 8.4 )
• Fluid Overload : Avoid in patients with or at risk for fluid and/or solute overloading. If use cannot be avoided, monitor daily fluid balance and electrolyte, concentrations and acid-base balance, as needed and especially during prolonged use. ( 5.6 )
• Refeeding Syndrome : Monitor severely undernourished patients and slowly increase nutrient intake. ( 5.7 )