Infuvite Adult

INFUVITE ADULT is a combination of vitamins indicated for the prevention of vitamin deficiency in adults and children aged 11 and older receiving parenteral nutrition. The physician should not await the development of clinical signs of vitamin deficiency before initiating vitamin therapy. INFUVITE ADULT is a combination of vitamins indicated for prevention of vitamin deficiency in adults and children aged 11 and older receiving parenteral nutrition ( 1 )

INFUVITE ADULT is contraindicated in patients who have

• An existing hypervitaminosis, or
• A history of hypersensitivity due to any vitamins or excipients contained in this formulation.
• Hypersensitivity to any of the vitamins or excipients ( 4 )
• Existing hypervitaminosis ( 4 )

• Risk of Aluminum Toxicity: For at risk patients (renal failure or those with prolonged therapy), consider periodic monitoring of aluminum levels ( 5.1 )
• Allergic Reactions: To thiamine may occur ( 5.2 )
• Hypervitaminosis A : Patients with renal failure or liver disease may be at higher risk ( 5.3 )
• Decreased Anticoagulant Effect of Warfarin: Monitor INR ( 5.4 , 7.1 )
• Interferes with Megaloblastic Anemia Diagnosis: Avoid during testing for this disorder ( 5.5 )
• Risk of Vitamin Deficiencies or Excesses: Monitor blood vitamin concentrations ( 5.6 )
• False Negative Urine Glucose Tests: Due to vitamin C ( 5.7 )

5.1Aluminum Toxicity

INFUVITE ADULT contains aluminum that may be toxic. Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solution, which contain aluminum. Research indicates that patients with impaired kidney function, including premature neonates who receive parenteral levels of aluminum at greater than 4 to 5 mcg/kg/day accumulate aluminum at levels associated with central nervous system and bone toxicity.