Indications
Elliotts B Solution is indicated as a diluent for the intrathecal administration of methotrexate sodium and cytarabine for the prevention or treatment of meningeal leukemia or lymphocytic lymphoma.
Contraindications
None known.
Warnings and precautions
Intrathecal administration of drugs such as methotrexate sodium and cytarabine should be performed by personnel skilled in the technique of lumbar puncture under the supervision of a physician who is experienced in the use of cancer chemotherapeutic agents. The labeling for methotrexate sodium and cytarabine should be consulted.
Pregnancy and breastfeeding
Usage in Pregnancy All components of Elliotts B Solution are normal body constituents. Animal reproduction studies have not been conducted with Elliotts B Solution.
Adverse reactions
Adverse reactions may occur with any given intrathecal injection due to the chemotherapy or the technique of intrathecal administration. (See product labeling for methotrexate sodium and cytarabine.) Preservative-free methotrexate sodium and cytarabine should be used to minimize adverse reactions due to preservatives. If an adverse reaction does occur, discontinue the administration, evaluate the patient, institute appropriate therapeutic countermeasures and, if possible, save the remainder of the unused solution(s) for examination.
Composition
- Active ingredients
- CALCIUM CHLORIDE 0.2MG/ML; DEXTROSE 0.8MG/ML; MAGNESIUM SULFATE 0.3MG/ML; POTASSIUM CHLORIDE 0.3MG/ML; SODIUM BICARBONATE 1.9MG/ML; SODIUM CHLORIDE 7.3MG/ML; SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE 0.2MG/ML
Official product information
Drugs@FDA lists the approved labels, letters and reviews for application NDA020577.
At a glance
- Brand name
- Elliotts B Solution
- Active substance
- calcium chloride
- Route
- Intrathecal
- Dosage form
- Injectable
- Applicant
- Lukare Medical LLC
- Status
- Prescription
- FDA approval
- 27 Sept 1996
- Application
- NDA020577-001



