| Trametinib Dimethyl Sulfoxide | 🇺🇸United States | 0.5MG, 2MG | tablet | Not marketed | Hikma |
| Mekinist | 🇺🇸United States | 0.5MG, 1MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, 2MG | tablet | Marketed | Novartis |
| Mekinist | 🇺🇸United States | 4.7MG | solution | Marketed | Novartis |
| Mekinist | 🇺🇸United States | 0.05MG BASE/ML | solution | Marketed | Novartis |
| Mekinist | 🇺🇸United States | 2MG | tablet | Marketed | Novartis |
| Mekinist | 🇪🇺European Union | | | Authorised | Novartis Europharm Limited |
| Spexotras | 🇪🇺European Union | | | Authorised | Novartis Europharm Limited |
| Spexotras 0,05 MG/ML Polvo Para Solucion Oral | 🇪🇸Spain | 5,3 mg | polvo para solución oral | Marketed | Novartis Europharm Limited |
| Mekinist 2 MG Comprimidos Recubiertos con Pelicula | 🇪🇸Spain | 2 mg | comprimido recubierto con película | Marketed | Novartis Europharm Limited |
| Mekinist 2 MG Comprimidos Recubiertos con Pelicula | 🇪🇸Spain | 2 mg | comprimido recubierto con película | Marketed | Novartis Europharm Limited |
| Mekinist 0,5 MG Comprimidos Recubiertos con Pelicula | 🇪🇸Spain | 0,5 mg | comprimido recubierto con película | Marketed | Novartis Europharm Limited |
| Mekinist | 🇮🇹Italy | | Compressa rivestita con film | Authorised | Novartis Europharm Limited |
| Spexotras | 🇮🇹Italy | | Polvere per soluzione orale | Authorised | Novartis Europharm Limited |
| Mekinist 1 mg filmomhulde tablet | 🇳🇱Netherlands | | Filmomhulde tablet | Authorised | Novartis Europharm Limited |
| Mekinist 2 mg filmomhulde tablet | 🇳🇱Netherlands | | Filmomhulde tablet | Authorised | Novartis Europharm Limited |
| Mekinist 0,5 mg filmomhulde tablet | 🇳🇱Netherlands | | Filmomhulde tablet | Authorised | Novartis Europharm Limited |
| Spexotras 0,05 mg/ml poeder voor drank | 🇳🇱Netherlands | | Poeder voor drank | Authorised | Novartis Europharm Limited |
| Mekinist | 🇨🇦Canada | 0.5 MG | Tablet | Marketed | Novartis Pharmaceuticals Canada INC |
| Mekinist | 🇨🇦Canada | 2 MG | Tablet | Marketed | Novartis Pharmaceuticals Canada INC |
| Mekinist | 🇨🇦Canada | 4.7 MG | Powder For Solution | Marketed | Novartis Pharmaceuticals Canada INC |
| Mekinist | 🇧🇷Brazil | | | Authorised | Novartis Biociencias S.A |
| Mekinist Film-Coated Tablets 2MG | 🇸🇬Singapore | 2mg | tablet, film coated | Authorised | Novartis (Singapore) Pte LTD |
| Mekinist® | 🇷🇸Serbia | 0.5mg | film tableta | Authorised | PredstavniŠTvo Novartis Pharma Services INC. Beograd (Novi Beograd) |
| Mekinist® | 🇷🇸Serbia | 0.5mg | film tableta | Authorised | PredstavniŠTvo Novartis Pharma Services INC. Beograd (Novi Beograd) |
| Mekinist® | 🇷🇸Serbia | 2mg | film tableta | Authorised | PredstavniŠTvo Novartis Pharma Services INC. Beograd (Novi Beograd) |
