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Medicines
Spain
Levodopa

AEMPS 1992

Levodopa, Carbidopa

SINEMET RETARD 50 mg/200 mg COMPRIMIDOS DE LIBERACION PROLONGADA

200 mg + 54 mg comprimido de liberación prolongadaSpainMarketedAuthorised 31 May 1992

Product informationAsk Osler about it

On this page

In other countries
Packs
Documents
Sources and licences

In other countries

The same active substances on other registers, the same brand first.

SinemetBrazil · Prodome Química e Farmacêutica LtdaSame brand
SinemetBrazil · Organon Farmacêutica Ltda.Same brand
SinemetCanada · 25 MG + 250 MG · Tablet · Organon Canada INC.Same brand
SinemetCanada · 25 MG + 100 MG · Tablet · Organon Canada INC.Same brand
Sinemet 100/10Canada · 10 MG + 100 MG · Tablet · Merck Canada INCSame brand
SinemetItaly · Compressa · Organon Italia S.R.L.Same brand
Sinemet 110, tablettenNetherlands · Tablet · N.V. OrganonSame brand
Sinemet 125, tabletten

More with the same substance on this register

Carbidopa/Levodopa Kern Pharma 25 MG/100 MG Comprimidos EfgLevodopa + Carbidopa · 27 mg + 100 mg · comprimidoSpain
Carbidopa/Levodopa Kern Pharma 25 MG/250 MG Comprimidos EfgLevodopa + Carbidopa · 27 mg + 250 mg · comprimido

Two medicines in one question?

Name two or more medicines and Osler runs an interaction check. A severe interaction is stated at the very top of the answer.

Netherlands · Tablet · N.V. Organon

Same brand

🇳🇱Sinemet 125, tablettenNetherlands · Tablet · Euro Registratie Collectief B.V.Same brand

🇳🇿SinemetNew Zealand · Tab 100 mg with carbidopa 25 mgSame brand

🇳🇿SinemetNew Zealand · Tab 250 mg with carbidopa 25 mgSame brand

🇳🇿Sinemet CRNew Zealand · Tab long-acting 200 mg with carbidopa 50 mgSame brand

🇸🇦Sinemet-110 TabSaudi Arabia · Merck Sharp & DohmeSame brand

🇸🇦Sinemet 25-250MG TabletsSaudi Arabia · Algorithm SALSame brand

🇸🇦Sinemet-275 TabSaudi Arabia · Merck Sharp & DohmeSame brand

🇺🇸SinemetUnited States · 10MG; 100MG, 25MG; 100MG, 25MG; 250MG · tablet · OrganonSame brand

🇺🇸Sinemet CRUnited States · 25MG; 100MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, 50MG; 200MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** · tablet, extended release · Organon LLCSame brand

🇭🇷Doporio 25 mg/250 mg tableteCroatia · Tableta · Orion Corporation, Orionintie 1, Espoo, FinskaSame form

🇭🇷Nakom 250 mg/25 mg tableteCroatia · tableta · Sandoz d.o.o., Maksimirska 120, Zagreb, HrvatskaSame form

🇭🇷Karbidopa/levodopa Medochemie 25 mg/100 mg tableteCroatia · Tableta · Medochemie Ltd., Constatinoupoleos Str. 1-10, Limassol, CiparSame form

🇮🇹Carbidopa e Levodopa AurobindoItaly · Compressa · Aurobindo Pharma (Italia) S.R.L.Same form

🇮🇹Levodopa Carbidopa HexalItaly · Compressa a rilascio prolungato · Sandoz S.P.A.Same form

🇸🇬Credanil 25/100 TabletSingapore · 25 mg + 100 mg · tablet · Goldplus Universal Pte LTDSame form

🇸🇬Credanil 25/250 TabletSingapore · 25 mg + 250 mg · tablet · Goldplus Universal Pte LTDSame form

🇸🇬Tidomet Forte TabletSingapore · 25 mg + 250 mg · tablet · Zyfas Pharma Pte LTDSame form

🇺🇸Carbidopa and LevodopaUnited States · 10MG; 100MG, 25MG; 100MG, 25MG; 250MG · tablet · Apotex INCSame form

🇧🇷CarbidolBrazil · Laboratório Teuto Brasileiro S/ASame substance

🇪🇺OnerjiEuropean Union · Tanabe Pharma GmbHSame substance

🇪🇺NumientEuropean Union · Amneal Pharma Europe LtdSame substance

🇷🇴DUODOPA 20 mg/ml+5 mg/mlRomania · 20mg/ml+5mg/ml · gel int. · ABBVIE DEUTSCHLAND GmbH & Co. KGSame substance

🇷🇴ISICOM 250 mg/25 mgRomania · 250mg/25mg · compr. · Desitin Arzneimittel GMBHSame substance

Packs

Pack	Code	Status
SINEMET RETARD 50 mg/200 mg COMPRIMIDOS DE LIBERACION PROLONGADA , 100 comprimidos	654765

Documents

The official texts, at the regulator.

Summary of product characteristicsAEMPS
Package leafletAEMPS
Register entryAEMPS

Sources and licences

Compiled by Prognia from the public register below; the register’s text is the official one.

Agencia Española de Medicamentos y Productos Sanitarios

Fuente de la información: Agencia Española de Medicamentos y Productos Sanitarios www.aemps.gob.es; CIMA medicamentos, acquired 11 October 2026 UTC; each source response/update date retained.

Licence: AEMPS explicit public open-data reuse for citizens and companies; source attribution and update date required · Added 12 Oct 2026

Report an error or request removalCorrections from the holder or the register are welcome.

Prognia shows this product information for reference and learning. It is not treatment advice and can lag behind the official text. Always check the current product information and local protocols before prescribing.

At a glance

Active substances: Levodopa, Carbidopa
Strength: 200 mg + 54 mg
Dosage form: comprimido de liberación prolongada
Route: vía oral
Register: Spain (AEMPS)
Status: Marketed
Status in the register: Autorizado, comercializado
Authorised: 31 May 1992
Registration: 59334
Marketing authorisation holder: Organon Salud S.L.
Procedure: National, MRP or DCP
Supply: Medicamento Sujeto A Prescripción Médica. Tratamiento De Larga Duración

🇪🇸Spain

AEMPSDoporio 25 MG/250 MG Comprimidos EfgLevodopa + Carbidopa · 250 mg + 27 mg · comprimido🇪🇸Spain

AEMPSDoporio 25MG/100 MG Comprimidos EfgLevodopa + Carbidopa · 100 mg + 27 mg · comprimido🇪🇸Spain

AEMPSDUODOPA 20 mg/ml + 5 mg/ml GEL INTESTINALLevodopa + Carbidopa · 2 g + 0,5 g · suspensión gastroentérica🇪🇸Spain

AEMPSSINEMET 25 mg/250 mg COMPRIMIDOSLevodopa + Carbidopa · 250 mg + 27 mg · comprimido🇪🇸Spain

AEMPSSINEMET PLUS 25 mg/100 mg COMPRIMIDOSLevodopa + Carbidopa · 100 mg + 27 mg · comprimido🇪🇸Spain

AEMPSSINEMET PLUS RETARD 25 mg/100 mg COMPRIMIDOS DE LIBERACION PROLONGADALevodopa + Carbidopa · 100 mg + 27 mg · comprimido de liberación prolongada🇪🇸Spain

AEMPSCarbidopa/Levodopa Aurovitas 25 MG/100 MG Comprimidos EfgLevodopa + Carbidopa · 100 mg + 27 mg · comprimido🇪🇸Spain

AEMPSCarbidopa/Levodopa Aurovitas 25 MG/250 MG Comprimidos EfgLevodopa + Carbidopa · 250 mg + 27 mg · comprimido🇪🇸Spain

AEMPSCarbidopa/Levodopa Kern Pharma 10 MG/100 MG Comprimidos EfgLevodopa + Carbidopa · 10,8 mg + 100 mg · comprimido🇪🇸Spain

AEMPSCarbidopa/Levodopa Kern Pharma 12,5 MG/50 MG Comprimidos EfgLevodopa + Carbidopa · 13,5 mg + 50 mg · comprimido🇪🇸Spain